Up to 1% of the population is estimated to have celiac disease, but even more are gluten-sensitive. Gluten is
rich in proline, which is highly resistant to hydrolysis mediated by proteases of the human gastrointestinal tract. Studies show that even when following a gluten-free diet, unintentional gluten intake can range from 200 mg/day to up to 3,000 mg/day, depending on the diet parameters. This can cause abdominal discomfort,
irregular bowel habits, skin concerns, imbalanced electrolytes, and nutrient malabsorption. Tolerase G® is a Prolyl Endoprotease derived from Aspergillus niger. According to preclinical studies, this specialized enzyme effectively breaks down residual gluten by cleaving proline-rich gluten epitopes. It has been shown in-vivo to efficiently break-down intact gluten (gliadin) after a meal; making it a superior option for those following a
gluten-free diet. Furthermore, it remains active under the harsh conditions of the stomach and is resistant to
pepsin. Undigested lactose is fermented by the intestinal microflora and can result in bloating, cramping, gas and diarrhea. In some cases, those who have gastric distress after consuming dairy products may not have an issue with lactose. Instead, the milk proteins or fat may be contributing to their discomfort or sensitivities. Beta-lactoglobulin occurs primarily in the whey fraction of milk. It is an acid-stable protein and therefore may not be broken down by pepsin and pancreatin. BioCore Dairy® includes proteolytic enzymes and lactase that breaks down the beta-lactoglobulin and lactose, which may help to relieve occasional bloating or gas that some people can experience from dairy consumption. Recent studies have shown lactose intolerance is correlated with low calcium intake and reduced bone mineral density. Supplemental enzymes such as those found in BioCore™ Dairy may help individuals consume calcium-rich dairy foods without discomfort. ‡ If you are on a controlled diet and/or under the care of a health professional for dairy and/or gluten digestion, continue to follow those recommendations. This product is not intended to substitute for the recommendations of a health professional.