Berberine UltraSorb provides Berbervis®, a berberine
phytosome with enhanced bioavailability. Several
randomized, placebo-controlled clinical studies indicate
that berberine promotes healthy insulin receptor function
and signaling, thereby supporting glucose metabolism.
Berberine supports the activation of AMP kinase (AMPK),
a central regulator of cellular energy homeostasis. This
master metabolic switch is involved with maintaining
healthy cardiovascular function, insulin signaling and
glucose metabolism.2 Berberine also helps to maintain
cholesterol levels already within the normal range.
Clinical studies show that daily doses of 1,000-1,500 mg of
standard berberine supports cardiometabolic parameters,
including lipid and triglyceride metabolism and healthy
blood flow. In a clinical study, berberine
supplementation of 500 mg twice daily for three months
provided clinically and statistically significant support for
healthy lipid profiles compared to baseline.6 Berberine
may also support endothelial function and colorectal
health. A pharmacokinetic study in healthy adults
reported that supplementation with 550 mg of Berbervis®
berberine phytosome was four times more bioavailable
compared to standard berberine.