Studies have indicated that GLA promotes healthyprostaglandin E1 (PGE1) production, which helps tosupport healthy joint function. Researchers at the University of Massachusetts Medical School, Worcester, reported that GLA helps support healthy cytokine activity, a mechanism that may be linked to both immune system support and joint health.1,2 A randomized, double blind, placebo-controlled trial reported statistically significant support for joint health in subjects supplementing with GLA from borage seed oil.3 PGE1 has also been associated with supporting and soothing the skin when used topically or taken orally.4